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KMID : 0359920110300060622
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Korean Journal of Nephrology
2011 Volume.30 No. 6 p.622 ~ p.628
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Hydration Status in Elderly Hemodialysis Patients: Bioimpedance Analysis
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Lee Shin-A
An Hye-Rim
Ryu Jung-Hwa
Yu Min-A
Ryu Dong-Ryeol
Kim Seung-Jung
Kang Duk-Hee
Choi Kyu-Bok
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Abstract
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Purpose: This study was aimed to compare hydration status between young and elderly end-stage renal disease (ESRD) patients on hemodialysis (HD) and to analyze factors related to overhydration.
Methods: We measured fluid status before a mid-week HD session in clinically stable 47 patients on maintenance HD using bioimpedance spectroscopy (BIS) device. In addition, weight and blood pressure (BP) were recorded during the treatment.
Results: Participants were divided into young (<65 years, n=32) and elderly (≥65 years, n=15) patients. In elderly patients, pre-HD diastolic BP, intracellular water (ICW), and lean tissue index (LTI) were significantly lower and extracellular water (ECW)/total body water (TBW) was significantly higher than in young patients. However, there were no differences in pre-HD body mass index (BMI), ultrafiltration volume, pre-HD systolic BP, TBW, ECW, and fat tissue index between the two groups. ECW/TBW ratio and LTI were significantly correlated with age. In a multivariate regression analysis, age and pre-HD pulse pressure were significantly associated with ECW/TBW.
Conclusion: Although BMI and TBW of elderly ESRD patients were similar to those of young patients, ICW and LTI were lower and ECW/TBW was higher in elderly patients than in young patients. Therefore, clinical manifestations related to overhydration may develop more frequently in elderly patients compared with young patients.
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KEYWORD
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Body composition, Edema, Renal dialysis, Aged
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